Alveofact 50mg Injection contains an active component called Phospholipid fraction from bovine lung. It is used as medication primarily in the treatment of respiratory distress syndrome (RDS) in premature infants. This condition occurs when the lungs don't produce enough surfactant, a substance essential for maintaining the lungs' elasticity and preventing alveoli collapse. In severe cases of pneumonia, especially in premature infants or newborns, where lung function is compromised, this medication might be used to support breathing. In some cases, this medication might assist with lung function when babies pass stool (meconium) while still in the womb and inhale it into their lungs before or during delivery, causing breathing problems.

Individuals with known severe allergies to components of the Alveofact 50mg Injection or any of its components should not receive it. In some cases, active or severe infections may be a contraindication to this medication due to the potential risk of worsening the infection or complicating the treatment. It might not be recommended for infants above a certain gestational age or weight threshold, as their lung maturity might not benefit from this intervention. If the patient has a severe bleeding disorder or an increased risk of bleeding, administering it may pose a risk of bleeding into the lungs or exacerbate bleeding issues, so should consult a healthcare provider before taking it. Alveofact 50mg Injection is primarily used in neonatal care and is not typically administered to older adults.

Neonatal respiratory distress syndrome (RDS).

Meconium aspiration syndrome.

Pneumonia.

Acute respiratory distress syndrome (ARDS).

Lung surfactant deficiency.

Alveofact 50mg Injection reduces surface tension at the air-liquid interface in the lungs' alveoli, preventing collapse during exhalation and ensuring these tiny air sacs stay open for gas exchange. Composed of lipids and proteins, it enhances lung compliance, making breathing easier. In conditions like respiratory distress syndrome (RDS) or surfactant deficiencies, surfactant replacement therapy supplements or replaces insufficient surfactant, improving lung function and preventing breathing complications.

Alveofact 50mg Injection should be used only when there is enough facility for ventilation and monitoring. This medicine should be administered via the intra-tracheal route. Your baby’s physician and nurse should constantly monitor to ensure that the right amount of oxygen is given. Dosing shall be stopped by the physician in case of a slow heartbeat or reduced oxygen in circulation and resumed only after the condition is stable.

Airway blockage

Infection

Allergic reactions

Pulmonary hemorrhage

Transient oxygen desaturation

Changes in heart rate

Breathing difficulties

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Alveofact 50mg Injection, reducing effectiveness by causing undesirable side effects.

Stored at controlled room temperature, between 2°C to 8°C

Keep away from moisture, heat, and light.

It should not be frozen.

Keep away from children and pets.

Ensure Alveofact 50mg Injection administration is conducted by trained healthcare professionals familiar with the procedure to minimize the risk of complications. Have proper ventilatory support available before and during administration to manage potential changes in oxygen levels or breathing difficulties. Continuously monitor your vital signs, oxygen levels, and respiratory status during and after administration to promptly address any adverse reactions or complications. Adhere strictly to aseptic techniques during administration to minimize the risk of infection. Ensure proper patient positioning to facilitate the administration process and minimize the risk of aspiration or airway obstruction. Conduct a thorough risk assessment, especially in cases of underlying lung conditions or compromised respiratory function, to determine surfactant therapy's potential benefits and risks.