Accentrix 2.3mg injection, contains the active ingredient Ranibizumab. It is an anti-neovascularisation agent in the class of medications called vascular endothelial growth factor A (VEGF-A) antagonists. It is used in adults to treat several eye diseases causing vision impairment. It is used to treat wet age-related macular degeneration (AMD, a persistent eye disease that causes loss of the ability to see straight ahead and may make it more difficult to read, drive, or perform other daily activities).

• Age-related macular degeneration
• Macular edema
• Diabetic macular edema and retinopathy
• Myopic choroidal neovascularization
• Retinal vein occlusion

Accentrix 2.3mg injection specifically recognizes and binds to a protein called human vascular endothelial growth factor A (VEGF-A) present in the eye. In excess, VEGF-A causes abnormal blood vessel growth and swelling in the eye, leading to impairment of vision in certain eye diseases. This medicine can block its actions and prevent this abnormal growth and swelling. This injection can help to stabilize and improve your vision.

Accentrix 2.3mg injection is administered as an injection into your eye by an eye doctor under a local anesthetic. Your doctor will decide the dose and frequency of the injection based on your disease condition. Do not self-administer the medicine.

• Pain and swelling in the eye
• Bleeding in the eye
• Blurred vision
• Urinary tract infection
• Skin rashes
• Discharge from the eye
• Tear of the layer in the back of the eye
• Flashes of light in the eye
• Temporary loss of sight
• Clouding of lens
• Infection of the eyeball

Do not use Accentrix 2.3mg injection if you are allergic to Ranibizumab or other ingredients of this medicine. Do not take this medicine if you have an infection in or around your eye and if you have pain or redness in your eye. Inform your doctor immediately if you develop symptoms such as eye pain or increased discomfort, worsening eye redness, blurred or decreased vision, an increased number of small particles in your vision, or increased sensitivity to light. Inform your doctor if you have a prior history of eye conditions or eye treatments or had a stroke before initiating the treatment.

• Store in a refrigerator (2°C – 8°C)
• Do not freeze
• Protect the medicine from light and excessive moisture.

The use of Accentrix 2.3mg injection in children and adolescents has not been established and is therefore not recommended. This medicine can be used for people of 65 years of age and over with dose adjustments. If the eye becomes red, sensitive to light, painful, or develops a change in vision, seek immediate care from an ophthalmologist. Your doctor will monitor the condition of your eye and, depending on how you respond to the treatment, will decide if and when you need to receive further treatment.