Bdparib 300mg tablet contains the active ingredient rucaparib. It is an anti-cancer medicine that belongs to the class of medications called PARP (poly ADP-ribose polymerase) inhibitors. It is used to help maintain the response to other treatments for certain types of ovarian cancer, fallopian tube (a tube that transports eggs released by the ovaries to the uterus), and primary peritoneal (layer of tissue that lines the abdomen) cancer that has reoccurred in adults who have previously completely responded or partially responded to other chemotherapy treatments. 

It is also used to treat certain types of cancer in people with specific gene (BRCA) changes who have received treatment with at least two other chemotherapy treatments. It is also indicated as maintenance therapy immediately after chemotherapy which has caused the tumor to shrink. Do not take Bdparib 300mg tablet if you are allergic to Bdparib or any of the ingredients. This medication can cause low blood counts; hence your healthcare professional will advise you to take certain blood tests before and every month during the treatment.  

Ovarian cancer

Fallopian tube cancer

Primary peritoneal cancer

Prostate cancer

Bdparib 300mg tablet is an inhibitor of poly Adenosine diphosphate-ribose polymerase enzymes, including PARP-1, PARP-2, and PARP-3, which play a role in DNA repair. It blocks an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. 

It is an orally available prescription drug. Your doctor will decide the dose and duration of Bdparib 300mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water. 

Rash

Constipation

Decrease in appetite

Diarrhea, indigestion

Nausea, vomiting

Changes in the blood count

Shortness of breath

Tiredness

Severe anemia

Hypersensitivity reactions

Sepsis (blood infection)

Pneumonia

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Bdparib 300mg tablet and reduce its effectiveness by causing undesirable side effects. 

Store at 20°C to 25°C

Protect the medicine from light and excessive moisture.

Keep the medicine out of reach of children and pets

If you forgot to take the tablet, take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

You may get sunburn easily during treatment with Bdparib 300mg tablet. Keep out of direct sunlight and wear protective clothing that covers your head, arms, and legs. Use sunscreen and lip balm with a sun protection factor (SPF) after consulting your doctor. If you vomit after taking the medicine, do not take an extra dose. Take your next dose at the regular time. Do not stop taking this medicine without talking to your doctor. Your doctor may do lab tests to check the therapy's effectiveness or monitor the unwanted side effects.