Bionase 10K Injection contains L-asparaginase. It is used to treat Acute Lymphoblastic Leukemia (cancer of white blood cells) in patients aged four months and above. In Acute Lymphoblastic Leukemia, the white blood cells called lymphocytes multiply in an uncontrolled and abnormal manner. This disorder is also known as Acute Lymphocytic Leukemia. 

This medicine should not be used if you have severe problems with your pancreas or allergic to any of the ingredients of this medicine. Talk to your physician if you are a diabetic patient as this medicine contains glucose. The common side effects of Bionase 10K Injection are muscle pain, nausea, infections, abdominal pain, and diarrhea.  

Use effective birth control during the treatment with Bionase 10K Injection and for at least three months after the last dose. Women should use contraception methods other than oral contraceptives.

Acute Lymphoblastic Leukemia (ALL)

Cancer cells need a substance called asparagine to survive. Bionase 10K Injection works by lowering the levels of asparagine in the body.

It will be given to you by your health care professional. Do not self-administer. Your physician will decide the dose and duration of your treatment based on the disease severity and other factors.

Severe allergic reactions

High blood sugar levels

Bleeding

Liver and nervous problems

Pain near your stomach (inflammation of the pancreas)

Blood clots in arm or leg

Pain, bruising, swelling, or hardening of the skin at the injection site 

Nausea

Muscle pain

Weight loss

Infections (fever, rapid heart rate, confusion, or a rash)

Difficulty breathing

Inflammation of the digestive tract

Diarrhea

Abdominal pain, discomfort

Headache

Tiredness

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Bionase 10K injection and can cause undesirable side effects.

Keep Bionase 10K Injection out of sight and reach of children.

Store in a refrigerator (2°C to 8°C).

This injection should be administered only by the doctor or nurse. Inform the doctor if the patient has any allergic response, blood pressure, kidney or liver problems, and medication taken for different medical conditions. Consult the doctor if the patient is pregnant or breastfeeding mother before taking this medication. Avoid driving while taking this medication, as it can cause dizziness. Avoid handling heavy machinery as the patient may lack concentration.