Bosutris 100mg Tablet contains the active ingredient bosutinib. It belongs to the group of medications called Tyrosine kinase inhibitors. It is indicated to treat adult patients with a type of leukemia known as Philadelphia chromosome-positive (Ph-positive) Chronic Myeloid Leukaemia (CML) who have been newly diagnosed or for whom earlier CML treatments have either failed or have not worked or are not suitable. Philadelphia chromosome-positive chronic myelogenous leukemia is a blood cancer in which the body produces too many of a specific kind of white blood cell called granulocytes. 

Low white blood cell count (leukopenia), headache, shortness of breath, joint pain, dizziness, cough, back pain, decreased appetite, respiratory tract infection, raised blood pressure, ringing in the ears (tinnitus), itching, acne, dehydration, taste change, sensitivity to light and fluid on lungs are the common side effects of Bosutris 100mg Tablet. Inform your doctor if any of these symptoms disturb you or persist.

Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML).

Bosutris 100mg Tablet works by inhibiting the activity of an enzyme called Bcr-Abl kinase that promotes the growth and spread of blood cancer (Ph+ CML). This helps to slow or stop the growth and spread of cancer cells.

Take Bosutris 100mg Tablet in the dose and duration prescribed by your doctor. Take this medicine once a day with food. Swallow it whole and avoid breaking or crushing the tablet. Do not handle or touch the broken tablets.

Blood disorders (bleeding, fever, bruising)

Stomach problems (stomach pain, vomiting, diarrhea, constipation, nausea)

Hepatitis B reactivation

Severe skin reactions

Liver problems (yellowing of white part of eyes and skin, tea-colored urine)

Heart problems (loss of consciousness, irregular heartbeat)

Low white blood cell count (leukopenia)

Headache, dizziness

Cough, shortness of breath

Joint pain, back pain

Decreased appetite

Respiratory tract infection

Increase in blood pressure

Ringing in the ears (tinnitus)

Itching, acne

Dehydration

Taste change

Sensitivity to light

Fluid on lungs

Inform your doctor about any medications you are taking or have taken before the treatment.

Keep Bosutris 100mg Tablet out of sight and reach of children.

Store between 20° to 25°C.

Women taking Bosutris 100mg Tablet are advised to use effective contraceptives like birth control during treatment and for one month (30 days) after the last dose. Check with your healthcare provider and inform them if you take any other medications, including over-the-counter and prescription medicines, vitamins, and herbal supplements. It is suggested to use sunscreen with a good sun protection factor (SPF) because you are sensitive to sun or UV rays while taking this medication. Do not eat or drink grapefruit-containing food products as this may increase the blood level in your body.