Celostatin LAR 30mg injection contains the active substance octreotide. It is a synthetic compound derived from somatostatin, a substance naturally found in the human body that inhibits the effects of certain hormones, such as growth hormones. It is used to reduce the amount of growth hormone produced by people with acromegaly (a condition in which the body produces too much growth hormone, causing enlargement of the hands, feet, and facial features; joint pain; and other symptoms) who cannot be treated with surgery, radiation, or another medication. 

• To treat acromegaly
• Relieve symptoms associated with some tumors of the GI tract
• To prevent complications following surgery of the pancreas gland
• To treat pituitary tumors that produce too much TSH

Celostatin LAR 30mg injection acetate, a cyclic octapeptide agent, inhibits growth hormone, glucagon, and insulin more effectively than the natural hormone somatostatin. The drug also reduces growth hormone and IGF-I (somatomedin C) in acromegaly, inhibits gallbladder contractions, reduces bile secretion, and suppresses thyroid stimulating hormone (TSH) secretion.

Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, an infusion of Celostatin LAR 30mg injection is given by either subcutaneous (under the skin) injection, intramuscularly (into the muscle of the buttocks), or intravenous (into a vein). A healthcare professional will always administer intravenous and intramuscular injections. If you are prescribed a subcutaneous injection, your doctor or other healthcare professional will explain how to inject the medicine under the skin.

• Diarrhea, flatulence
• Abdominal pain
• Back pain
• Tiredness
• Headache, nausea
• Increased heart rate
• Changes in heart rhythm
• Increased or decreased blood sugar levels
• Changes in thyroid levels
• Vitamin B12 deficiency
• Gall stones

Do not use this medicine if you are allergic to octreotide or any of the other ingredients of this medicine. Inform your physician if you have gallstones, high or low blood sugar levels, vitamin B12 deficiency, and liver diseases. Celostatin LAR 30mg injection may lower your heart rate, and very high doses can cause abnormal heart rhythm, so your doctor may monitor your heart function regularly during the treatment. Inform your physician if you are pregnant or breastfeeding before initiating the treatment.

• Store the Celostatin LAR 30mg injection in the refrigerator at 2°C to 8°C
• Do not freeze
• Protect the medicine from light and excessive moisture.
• Keep the medicine out of reach of children and pets
• If you forgot to take the injection, inform your healthcare professional immediately and reschedule the appointment.

Regularly check blood sugar levels and inform your physician if you notice any changes such as increased or decreased blood sugar level. Female patients of reproductive potential use an alternative non-hormonal method of contraception, such as condoms, when the oral form of this medicine is used. This medicine is given as a shot under your skin, into a muscle, or into a vein, based on your condition. This medicine may improve fertility in women and can cause unwanted pregnancies. Talk to your doctor if you have any concerns.