Cresp 40mcg injection contains the active ingredient Darbepoetin Alfa. It is an antineoplastic drug that belongs to the class of medications called hematopoietic growth factors. It is used to treat anemia (lower than normal RBC) in people with chronic kidney disease. It is also indicated to treat anemia caused by chemotherapy in people with certain types of cancer. The symptoms of anemia are fatigue, weakness, and shortness of breath.

To treat anemia in chronic kidney failure

To treat anemia caused by chemotherapy

Cresp 40mcg injection is an erythropoiesis-stimulating protein produced by recombinant DNA technology. It is closely related to erythropoietin and stimulates erythropoiesis by the same mechanism, and both agents bind to progenitor stem cells stimulating the production/differentiation of red blood cells. It works by causing the bone marrow to make more red blood cells.

This injection is to be given under the skin (subcutaneous). Your doctor, nurse, or other healthcare professional will train you on how to inject yourself with this pre-filled pen. Do not try to inject the pre-filled pen if you are not well-trained. Never inject the medicine into your vein. If you need help to inject the medicine, visit the nearby hospital or clinic.

Swelling in the face and body

Low blood pressure

Abdominal pain

Shortness of breath

Cough

Heart problems

Severe skin reactions

Anemia

Seizure attack

Lung problems

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Cresp 40mcg injection and reduce its effectiveness by causing undesirable side effects.

Store in a refrigerator (2°C to 8°C).

Do not freeze. Store in the original package to protect from light.

Keep the injection away from the reach of children and pets.

If you have missed any dosing appointments, inform your doctor and schedule immediately.

Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin. A nurse or other health provider will give you this medicine. You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to. 

Do not shake the vial or syringe. You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, heart disease, heart failure, a blood disorder, cancer, any infection, bleeding, or a history of blood clots, heart attack, stroke, or seizures.