Crizalk Crizotinib 250mg Capsules 60's

The Crizalk 250mg capsule contains the active substance Crizotinib. It is an antineoplastic drug that belongs to the class of tyrosine kinase inhibitors. This medicine is prescribed to treat patients with a type of lung cancer called anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC) that is locally advanced or metastatic (spread outside the lungs or to other parts of the body). Do not take Crizalk 250 mg if you are allergic to Crizotinib or any other ingredients of this medicine. Before initiating the treatment, inform your physician if you have had kidney, stomach, heart, or liver problems. 

Notify your doctor if you have reduced white blood cells, abnormal heart tracing after ECG, vision problems, or if you take other medications. Report your doctor immediately if you are planning to get pregnant or think you may be pregnant. Talk to your doctor about effective contraceptives. Use effective birth control during the treatment because oral contraception is ineffective with this medicine, and use it at least for 90 days even after completing the therapy with Crizalk 250 mg. It is advised to get suggestions about fertility concerns from your doctor. This medication is not recommended for adolescents and children under 18 years of age. Use sunscreen or protective clothing to cover the skin and protect it against sunburn.

Anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC).

Crizotinib in Crizalk 250mg by Pfizer is a tyrosine kinase inhibitor that works by blocking the activity of the anaplastic lymphoma kinase (ALK) protein. It specifically targets the abnormal protein and blocks its activity, slowing down or stopping the growth and spread of cancer cells.

Take the Crizalk 250 mg capsules at about the same time each day. The recommended dose is one capsule of 250 mg taken orally twice daily. Swallow the capsules whole and do not crush, chew, dissolve, or open the capsules. Your physician will choose the Crizalk 250 mg dosage and administration frequency based on the medical condition because it differs for each person.

Serious:

• Pain on the right of the stomach
• Partial or full loss of vision
• Lowered WBC
• Low heart rate.
• Swelling of the lungs.
• Breathlessness
• Cough with or without mucus

Common:

• Sensitivity to sunlight.
• Diarrhea
• Fever
• Constipation
• Nausea
• Increased liver enzymes
• Decreased appetite, tiredness (fatigue)
• Dizziness
• Neuropathy (weakness, tingling, or numbness in the nerve)
• Dysgeusia (taste disorder)
• Hypophosphatemia (low levels of phosphate in the blood)

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications such as Erythromycin, Diltiazem, Verapamil, and other medications may interact with Crizalk 250 mg and reduce its effectiveness by causing undesirable side effects. 

• Store at room temperature (15-30°C) in the original container.
• Keep this medicine out of the sight and reach of children.

• Blood Counts: Inform your doctor if you experience reduced white blood cells (neutropenia) or red blood cells (anemia), which can cause weakness, breathlessness, or pale skin.

• Heart Monitoring: Your doctor may perform an electrocardiogram to check heart function and monitor for a slower heart rate.

• Medication Adherence: Take the Crizalk 250 mg capsule daily as prescribed by your doctor without skipping doses.

• Sun & Other Precautions: Avoid excessive sunlight due to photosensitivity, and report stomach issues, ankle swelling, or other unusual symptoms to your doctor promptly.