Darzalex 400mg injection is a targeted therapy for cancer containing the active ingredient Daratumumab, which belongs to the group of medicine called monoclonal antibodies. Monoclonal antibodies are proteins that recognize and attach to the specific target, killing the cancer cells. It is used to treat a type of cancer called multiple myeloma (bone marrow cancer) in adults 18 years or older. Report to your doctor if you have ever had a hepatitis B infection; this medicine may cause the hepatitis B virus to become active again. This medicine can decrease platelets (helps in blood clotting) and white blood cell counts (helps fight infections). 

Do not take a Darzalex 400mg injection if you are allergic to Daratumumab or other medicine ingredients. This medicine is not recommended for children and adolescents. Inform your doctor if you get any infusion-related reactions, such as swollen face, lips, mouth, tongue, or throat. If you notice any infusion reactions, you need other medicine, or the infusion will be slowed down or stopped.

Treatment of Multiple myeloma

Darzalex 400mg binds specifically to a protein called CD38 found on the surface of multiple myeloma cells. This binding can trigger the immune system to attack and kill the cancer cells.

A trained doctor or nurse should only administer Darzalex 400mg. Do not self-administer the injection. Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for unwanted side effects.

Infusion reactions (itching, wheezing, chills, fever, throat tightness, runny nose, headache, low pressure)

Changes in blood tests

Decrease in blood cell counts

Nausea, vomiting

Back pain, muscle spasms

Diarrhea

Tiredness

Shortness of breath

Upper respiratory tract infection

Tingling, numbness, or pain

Constipation

Trouble sleeping

Dizziness

Joint pain

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional, supplements, and herbal products. In particular, tell your doctor if you are taking medicines for blood pressure or other heart conditions. Certain medications may interact with Darzalex 400mg and reduce its effectiveness by causing undesirable side effects.

Store Darzalex 400mg in the refrigerator (2°C to 8°C)

Do not freeze

keep the injection away from the reach of children and pets.

If you have missed any dosing appointments, inform your doctor and schedule immediately.

If you experience any symptoms mentioned above, consult your doctor immediately. While undergoing treatment, use effective contraception and continue it for three months after stopping treatment. Darzalex 400mg is not recommended for children and adolescents under 18 years. Do not freeze the medicine. Before starting the treatment, inform your doctor about every underlying medical condition. Talk to your physician if you are on a salt-controlled diet, as this medicine contains sodium.