Endoxan Asta 1gm Injection is a chemotherapy drug containing the active constituent cyclophosphamide. It is used to treat various malignancies (abnormal production of cells is called cancer, and if they spread to other organs, they are called malignancies). Endoxan Asta 1gm Injection can be used to treat malignant lymphomas (cancers that start from the lymphatic system of the body- vessels, fluid, and lymphoid tissue) such as Hodgkin’s disease, lymphocytic lymphoma, and mixed-cell type lymphoma. 

It is used to treat leukemias, neuroblastoma, ovarian cancer, retinoblastoma, and breast carcinoma. It can also treat Minimal Change Nephrotic syndrome in pediatric patients (kidney disease in which large quantities of protein are lost in urine). Endoxan Asta 1gm Injection is contraindicated in pregnancy, patients with acute infections, urinary tract infections, urinary outflow obstruction, and bone marrow disorders.  

Treatment with this medicine may lead to immune suppression, bone marrow failure, cardiotoxicity, renal toxicity, pulmonary toxicity, and secondary malignancies. Inform your doctor if you have pre-existing kidney disease, immune conditions, cardiac disorders, or liver diseases.

Malignant lymphomas

Leukemias

Retinoblastoma

Carcinoma of breast

Ovarian cancer

Mycosis fungoides

Minimal Change Nephrotic Syndrome in Pediatric Patients

Endoxan Asta 1gm Injection Injection slows or stops the growth of cancer cells by damaging the hereditary material (DNA and RNA) of the cancer cells. In nephrotic syndrome, it works by suppressing the body’s immune system.

Endoxan Asta 1gm Injection will be administered intravenously by healthcare professionals experienced in cancer chemotherapy. Do not self-administer.

Infections

Immune suppression

Blood disorders

Allergic reactions

Abnormal liver function

Inflammation of the bladder

Kidney diseases

Blood in urine

Sterility

Impaired wound healing

Nausea, vomiting

Low white blood cell count

Diarrhea

Hair loss

Fever

Weakness

Inflammation

Dizziness

Blurred vision

Amenorrhea

Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Endoxan Asta 1gm Injection and cause potential side effects.

Keep out of sight and reach of children. Store vials below or at 25°C.

Inform the doctor if the patient has any kidney, liver, or heart problems and medication taken for different medical conditions. It causes immune suppression, and hence inform the doctor if there are any immune problems. Avoid this medication if the patient is pregnant or breastfeeding mother. The patient undergoing treatment with Endoxan Asta 1gm Injection may have dizziness and blurred vision. Consult your doctor before driving and handling heavy machines.