Imfinzi 500mg injection is an anticancer drug belonging to the class of Anti-PD-1 monoclonal antibodies, containing the active ingredient Durvalumab. It is used to treat non-small cell lung cancer(has not spread outside your chest ), small cell lung cancer(has spread within your lungs), and biliary tract cancers(cancer of the bile ducts). Tell your doctor if you have had an organ transplant, liver problems, lung or breathing problems, or autoimmune disease (the body’s immune system attacks its own cells) before taking this injection.

The common side effects that are likely to occur with this injection are cough, upper respiratory tract infections, feeling tired, shortness of breath, inflammation in the lungs, and rash. This medicine may increase the risk of developing immune-mediated adverse reactions like pneumonitis, colitis, hepatitis, endocrinopathies, and nephritis which have been reported.

Non-Small Cell Lung Cancer

Small Cell Lung Cancer

Biliary Tract Cancer

It works by blocking a protein called programmed death-ligand 1 (PD-L1), which is found on the surface of certain cancer cells. When PD-L1 binds to its receptor on T cells, it can inhibit the immune system's ability to recognize and attack cancer cells. By blocking the interaction between PD-L1 and its receptor, this drug allows T cells to recognize and attack cancer cells more effectively. It helps the immune system to fight cancer and potentially slow or stop its growth.

Imfinzi 500mg injection is a prescription drug available in injection form. This injection will be given intravenously into a vein in your arm or hand by a healthcare professional in a hospital setting. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. During the infusion, you will be monitored for any side effects or reactions to the medication. The infusion usually takes a few hours to complete, and you may need to receive multiple infusions over the course of several weeks.

Infection (chills, increased temperature)

serious lung infections (pneumonia)

fungal infection in the mouth

tooth and mouth soft tissue infections

flu-like illness

an overactive thyroid gland that can cause a fast heart rate or weight loss

inflammation of the lungs (pneumonitis)

hoarse voice (dysphonia)

abnormal liver tests (aspartate aminotransferase increased; alanine aminotransferase increased), night sweats

muscle pain (myalgia)

abnormal kidney function tests (blood creatinine increased)

painful urination

swelling of the legs (oedema peripheral)

reaction to the infusion of the medicine that can cause fever or flushing

Cough

upper respiratory tract infections

feeling tired

shortness of breath

inflammation in the lungs

rash

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Imfinzi 500mg injection and reduce effectiveness by causing undesirable side effects.

Store Imfinzi 500mg injection in the refrigerator at (2°C to 8°C).

Do not freeze.

Keep it out of reach from children.

Imfinzi 500mg injection has the tendency to cause harm to unborn fetus. Inform your healthcare provider before starting this treatment if you are pregnant, or have a partner who can become pregnant. Your healthcare provider will conduct a pregnancy test before you start treatment with this drug. Discuss effective birth control methods with your healthcare provider and use them during treatment and for 8 weeks after your last dose. It is not known if this drug passes into breast milk. Hence, it is not recommended to breastfeed during this treatment. This drug can increase your risk of sunburn and skin damage, so it is important to wear protective clothing and sunscreen while moving outdoors. If you experience any gastrointestinal symptoms, such as diarrhea, abdominal pain, or nausea, be sure to inform your doctor immediately so that he may prescribe you antiemetic medicines also to prevent the symptoms.