Sorafenat 200mg Tablet belongs to the anti-cancer group of medicines. It consists of the active ingredient Sorafenib, which is indicated for advanced renal cell carcinoma (kidney cancer), advanced hepatocellular carcinoma (liver cancer) in patients ineligible for surgery, and differentiated thyroid carcinoma (thyroid cancer) in patients who are not responsive to radioactive iodine therapy. 

Diarrhea, tiredness, stomach pain, nausea, weakness, rashes, flu-like illness, appetite loss, nausea, weight loss, and low blood calcium levels are common side effects of Sorafenat 200mg Tablet. Inform your doctor if any of these side effects disturb or persist with you. 

Inform your doctor if you are allergic to this tablet and its ingredients. Before starting treatment with this tablet, you should tell your physician if you have heart problems, chest pain, bleeding problems, high blood pressure, or have had or are about to have surgery. Use effective contraception during the therapy and for 6 months after the last dose if you are a woman or 3 months after the last dose if you are a man.

Advanced renal cell carcinoma

Advanced hepatocellular carcinoma that cannot be surgically treated

Advanced papillary and follicular Hurtle cell thyroid carcinoma

Sorafenat 200mg Tablet works by inhibiting multiple receptor tyrosine kinases (enzymes), primarily vascular endothelial growth factor receptors and platelet-derived growth factor-β receptors. This prevents the development of blood vessels in tumor cells (angiogenesis) and arrests the growth and spread of the tumor cells to other organs.

Take the Sorafenat 200mg tablet without food (1 hour before or 2 hours after a meal). Swallow with a glass of water. Do not break, crush or chew the tablets.

Stevens Johnsons Syndrome and toxic epidermal necrosis

Decreased blood flow to the heart

Increased risk of bleeding (blood in urine, stool, vomit, cough, etc.)

High BP

Skin problems

Liver problems

Problems in wound healing

Nausea, stomach pain, diarrhea

Tiredness and weakness

Infection

Hair thinning and patchy hair loss

Rash

Weight loss

Loss of appetite

Low levels of calcium in the blood

Flu-like illness

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, or herbal products that you are taking or have taken before the treatment. Certain medications tend to interact with Sorafenat 200mg tablet and decrease its effectiveness.

Store below 30°C in a dry place.

It is advised to seek immediate medical attention if you have swelling in your lower legs, fast heartbeats, or trouble breathing. It may be a sign of heart problems. It may result in bleeding hence inform your doctor if you see blood in stools or urine.