Trabec 1MG Infusion contains the active ingredient Trabectedin. It is an antineoplastic drug that belongs to the class of medications called alkylating agents. It is used to treat Liposarcoma (a type of cancer that starts in fat cells) or Leiomyosarcoma (cancer that begins in smooth muscle tissue) that has spread to other parts of the body and cannot be treated with surgery in individuals who have already received treatment with certain anti-cancer medications. It is also indicated to treat ovarian cancer that has reoccurred after at least 1 previous therapy and not responding to other treatments.  

Do not take Trabec 1MG Infusion if you are allergic to Trabectedin or any other ingredients of this medicine, if you have serious infections, if you are breastfeeding, and if you will receive a yellow fever vaccine. Inform your physician if you have an active infection, or suffered from any infections, liver disease, kidney problems, or heart diseases. This medicine may impair fertility, discuss with your doctor before planning for pregnancy.  

Report to your physician if you face any symptoms of sudden difficulty in breathing, fever, redness or flushing of the skin, or a rash, nausea, or vomiting after the administration of the injection. Trabec 1MG Infusion is not recommended for children and young people under 18 years of age. Use an effective method of contraception while being treated with this injection. Avoid pregnancy and breastfeeding during the treatment.

Liposarcoma or Leiomyosarcoma

Trabec 1MG Infusion is an alkylating agent, that causes a disruption in the tumor cell cycle and cell death by initiating a cascade of events triggered by the binding of certain nucleobases in the DNA preventing the multiplication of tumor cells. It works by slowing or stopping the growth of cancer cells in the body.

It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. It is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors. Your doctor will give you certain medications to lessen the chance of getting side effects from the Trabec 1MG Infusion treatment.

Constipation

Decrease in appetite

Diarrhea

Nausea, vomiting

Anemia

Decreased albumin levels

Decreased platelet count

Headache

Shortness of breath

Tiredness 

Heart problems

Skin rashes

Liver problems

Severe muscle pain

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, vaccines, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Trabec 1MG Infusion and reduce its effectiveness by causing undesirable side effects.

Store Trabec 1MG Infusion in the refrigerator (2°C to 8°C).

Do not freeze.

Keep the injection away from the reach of children and pets.

If you have missed any dosing appointments, inform your doctor and schedule immediately.

Trabec 1MG Infusion may interfere with vaccines, inform your physician before taking yellow fever vaccine or any other vaccines. This injection may cause severe birth defects if taken during pregnancy. Female patients with reproductive potential should use effective contraception during the treatment. Male patients with female partners with reproductive potential should use effective birth control methods during the treatment and for at least 5 months after their last dose. Do not breastfeed during treatment with this injection. Your doctor may advise you to take certain tests to check for the effectiveness of the therapy.